Health & Wellness

NIH’s Genome Chief Says Genomics Is Evolving and Doctors Need Extra Training on It

Published

3 years ago

April 8, 2023

NIH’s Genome Chief Says Genomics Is Evolving and Doctors Need Extra Training on It

Researchers proceed to manufacture strides within the topic of genomics, bringing revolutionary treatments and diagnostic instruments to sufferers, whereas suppliers and regulators grapple with the ethical disorders that arise this ability that. As segment of our occasional series of interviews with federal healthcare officials, MedPage This present day Washington Editor Joyce Frieden sat down with Eric Inexperienced, MD, PhD, director of the Nationwide Human Genome Review Institute in Bethesda, Maryland, to chat about his career, basically the most up-to-date advances in genomics, and his hopes for the scheme in which forward for his chosen topic.

The next transcript of the interview, which used to be performed with a public relatives person show, has been edited for length and readability.

Thanks for taking the time to focus on with us! Repeat us about yourself and the scheme in which you ended up for your most up-to-date region.

Eric Inexperienced, MD, PhD: You’re welcome! I used to be born and raised in St. Louis, and then went off to the University of Wisconsin for my undergraduate stage. I came relief to Washington University [in St. Louis] for the MD/PhD program, and then determined to practice in clinical pathology. I had a bit little bit of a vague hobby on this very early topic — molecular diagnostics.

After the principle year, you hurry off and cease postdoctoral analysis 90% of the time, and this used to be in 1988, a year after the note “genomics” used to be coined and a pair of years earlier than the Human Genome Project used to be launched. And I came about to be at Washington University, where there were some world class leaders in genomics. And so I joined one amongst the labs there, and the comfort is history attributable to I form of made a career of it. A year and a half to 2 years into [my postdoc there], the Human Genome Project began and Washington University used to be funded as one amongst the principle genome facilities. I used to be on the entrance line, working one amongst two major initiatives as a postdoc, and within the discontinuance joined the college.

When Francis Collins came here to yell this institute, he [recruited me], so I came here 29 years ago, and for virtually half that time, I’ve been the director.

For your time on the Institute, what progress has been made within the exercise of genomics for diagnosing and treating illness?

Inexperienced: Let’s starting up with most cancers, which is a illness of the genome. After I went to clinical college, so grand of what you did spherical most cancers used to be plug by what segment of the body you decrease it out of. Ought to you decrease it out of the breast, it always situation you down this route, nonetheless within the event you decrease it out of the liver, it be something else, and within the event you decrease it out of a bone, it be something else.

Recently, within the event you ask an oncologist most steadily, “Is it more informative to grab where I decrease it out, or if I gave you a genomic signature of that tumor?,” they wish the signature. On account of what we’re finding out more and more is that that is largely the most intriguing technique to foretell prognosis and decide out basically the most intriguing alternate choices for therapy. The literature is now stuffed with fable after fable of “We found these tumors within the bone and they also ogle admire a breast most cancers and there is now not any major breast most cancers, nonetheless we handled it admire it used to be a breast most cancers and it labored.” So the tissue of starting up do is changing into grand less foremost.

The 2nd example is rare genetic diseases, alongside with some famed ones admire sickle cell, cystic fibrosis, and Huntington’s illness. They’re rather straight forward from a genomic stage attributable to it be assuredly the breakage of a single gene via a mutation in one gene.

When the Genome Project began, we handiest knew about 61 of those diseases for which we knew what gene used to be mutated. Nonetheless now we know virtually 6,000. That has situation up as a circumstance where will bear to you come across a affected person, especially a perplexing affected person — and some folk were undiagnosed for decades — you excellent sequence the genome. It be now not that expensive, lower than $1,000, and the diagnostic yield is going up annually. We’re bettering and greater at figuring this out. Most steadily it supplies you insights on be taught how to accommodate, and customarily it ends a affected person’s diagnostic odyssey — as a minimal they’ve a prognosis.

The third example is with prenatal genetic making an strive out, where they’re largely procuring for faulty chromosomal abnormalities — aneuploidy, admire trisomy 21, famously is called Down syndrome. For that you just are going to like a respectable technique to entry fetal DNA, which [previously] used to be both an amniocentesis or chorionic villus sampling. Both of these is invasive, and I’m told it be now not good, and likewise there is a itsy-bitsy distress of [miscarriage].

What’s varied now? Neatly, biologically, nothing’s varied, nonetheless technologically, all the pieces’s varied. It turns out that the placenta naturally sheds itsy-bitsy quantities of cell-free DNA into the maternal blood. Twenty years ago, we had no ability to detect those teeny bits of DNA that naturally hurry with the waft spherical in maternal blood, nonetheless now we cease attributable to we now bear got new methods for sequencing DNA. So now, the pregnant person gets a blood blueprint, they rob a further tube at 8 to 12 weeks, and they also separate the liquid segment — it has cell-free DNA, some from the fetus and some from Mom. They sequence the DNA exquisitely sensitively and they also excellent ogle for whether or now not all the pieces is uniform. If they detect anything that is largely novel, they’ll repeat it, and ogle more fastidiously, and they also could well cease an amniocentesis.

Here is is called non-invasive prenatal making an strive out, or NIPT. And the industrial sector saw this as a substantial different, so there were more than one firms providing this, and it has pushed the worth down. The obstetrics authentic societies bear talked about here is wide despite the real fact that their members are shedding money, attributable to they realize the test doesn’t wish to be so invasive. As a result, 5 million to 7 million pregnant ladies folk a year worldwide are conception to be getting this non-invasive test.

The fourth do is pharmacogenomics — insist I’m hypertensive and I’m going to rob a hypertensive treatment and I in point of fact bear a series of 10 treatment. Which drug will bear to I rob? It has nothing to cease with the pathophysiology of the hypertension; it has to cease with my drug metabolism pathways and the scheme in which I obvious treatment out of my machine. It will likely be that Drug A, I obvious very poorly so I change into toxic as soon as I rob it, and Drug B I’d “hyper-obvious” so it be couldn’t be effective, and Drug C is one which I obvious completely beautiful so I’m going to defend real via the therapeutic differ. So the foremost distinction is pharmacogenomics.

How are things coming into phrases of clinician consciousness? Are ample doctors attentive to and the utilization of genomics for clinical making an strive out and therapy?

Inexperienced: No, they’re now not, and that is the explanation a wide precedence for the Institute. And we’re working very arduous. It be now not handiest clinical education — it entails the general healthcare starting up ecosystem, which as , oftentimes is now not face to face alongside with your doctor; it be face-to-face alongside with your nurse, your pharmacist, or your doctor assistant. There could be a full team that we want to be transferring alongside. And naturally, we’re doing this at a time where the science is transferring very snappy.

I in point of fact bear a son who is a Third-year clinical pupil. I wish I could well insist that what he realized within the principle 2 years of clinical college used to be ample genomics to be moving for the future that his father’s describing, nonetheless he did now not. And he’s at a prime-fee clinical college. I’m now not faulting the college; here’s a arduous distress for them. We won’t excellent insist, “Medical colleges, it be your distress,” attributable to making an strive to trade the clinical college curriculum is admire making an strive to trade the federal government. Nonetheless these students are vivid, lifelong learners, so we now bear got to position out the instruments to abet them be taught genomics as they hurry alongside.

No longer to mention the real fact that heaps of physicians out there, alongside with my clinical classmates who’re practising treatment, by no scheme heard the note “genomics” as soon as in clinical college, since the note didn’t exist till lawful after they graduated. So it be one amongst the things we’re doing.

I cease mediate more and more clinicians are changing into wide awake. Extra sufferers with rare diseases are getting referred to clinical specialists or other physicians who cease know about getting the genome sequenced. I used to be told now not too long ago that it used to be conception that within the US, roughly 25,000 sufferers with rare stipulations or suspected rare stipulations will win their genome sequenced annually, and that number can even very correctly be matched internationally.

You’ve got talked about genomics’ progress in making an strive out. What about for therapy of illness?

Inexperienced: It used to be believed that one of the most earliest gene therapy successes would reach with with things which are in blood, and the trigger of that is attributable to bone marrow is available — painful, nonetheless accessible. So let’s discuss two extremes, each diseases where there used to be heaps of hype: sickle cell and cystic fibrosis. And within the case of sickle cell, the tissue where the general motion is, is within the blood, which is made within the bone marrow. In cystic fibrosis there are many organs alive to, nonetheless most seriously the lungs, which are now not very accessible or [easy to culture]. And so it’s intriguing to leer what has performed out.

Ought to you ogle at sickle cell illness, the successes we’re seeing now could well be it’s essential well rob a affected person with sickle cell, rob away some of their bone marrow the utilization of the gene bettering diagram [known as] CRISPR to repair the sickle cell mutation within the laboratory, and then you’re hanging their cells relief in their bone marrow. Then they’re making regular hemoglobin and they also’re cured.

Within the case of cystic fibrosis, there is aloof hope spherical gene therapy, nonetheless in point of fact the things which bear created progress in most up-to-date years were the reach of most up-to-date treatment.

Are there guardrails that wants to be place aside spherical this technology?

Inexperienced: I mediate there are some very correctly talked about guardrails spherical genome bettering. It is the adaptation between somatic cells — those are body cells — bone marrow, mind cells, that is all body and that is the explanation beautiful. You’ll want to well cease heaps of stuff with that and it be now not as touching on. It be will bear to you hurry to the germline; that is where the guardrail is. Close now not hurry to the germline, or sperm or egg, and manipulate those. The gentleman in China, he created these twins and made the principle CRISPR infants. The Chinese language are keeping it hush-hush what their fate is, nonetheless there is heaps of reasons to be nervous.

So repeat us about your funds. How wide is it, and what cease you utilize the money on?

Inexperienced: We’re a rather itsy-bitsy institute at NIH, almost definitely within the backside 5 or six in phrases of dimension, despite the real fact that we mediate we now bear got an intellectual footprint that is rock-superstar in phrases of dimension. I mean, genomics is in each insist. Some folk mediate I need to bear 10% or 20% of the NIH funds attributable to genomics is in each insist, nonetheless we’re handiest 1.4% of the NIH funds. It be aloof a wide chunk of trade — about $656 million. Will we would like it’d be greater? Needless to insist, nonetheless by and dapper we now bear had a funds that has allowed us to cease a wide quantity. And we leverage plenty more exercise in attributable to we’re invited to heaps of collaborative initiatives going on in other substances of NIH.

Of that $656 million, 20% of it stays here for a pretty wide on-campus program we now bear got in genetics and genomics. About 5% of it’s to speed the Institute, and 75% goes out to “extramural” grants — we’re giving out grants all at some stage within the world, largely within the US, nonetheless some in another country as correctly. We’re doing all the pieces from creating technologies for sequencing and inspecting DNA, to creating records sources to sharing all this records worldwide, to figuring out how every nucleotide, every unfriendly genome works, and figuring out how variants in our DNA affect our health and illness.

How cease you’re feeling relating to the position that sufferers are playing in directing funding for illness analysis?

Inexperienced: What’s occurring at some stage in all of biomedical analysis — and NIH is main on this as grand as everyone else — is to bring the sufferers into the dialog more. I mediate NIH could well be the principle to insist that for too long, we saved at an arm’s distance from sufferers. And within the discontinuance, that is great now not going to work, in particular for sufferers with rare diseases. And by the scheme in which, this is why they’re aggregating; you’re seeing more and more rare illness communities aggregating together, and that is the explanation what’s main to major programmatic adjustments.

Factual this morning I used to be at a meeting with [one NIH institute director] who spends hours a week having to accommodate varied advocacy groups in [his disease] personnel. I build now not take care of advocacy groups attributable to I build now not obtain any illness. That can perhaps well even be each a blessing and a curse.

Of us on the general elevate concerns relating to privateness in phrases of genetic test results. Is that a insist for you?

Inexperienced: I mediate customarily folk will gash out genetics and fabricate it seem admire it be fully varied in phrases of privateness, and I impress it has some variations attributable to if nothing else, it supplies you insights about your relatives. Nonetheless, there are heaps of different things about you besides genetics, and our clinical files are getting more and more digital. Boy, it’s essential well be taught plenty just a few person excellent by taking a ogle at their clinical files! Of us seem very pondering about any individual seeing their genome sequence, nonetheless they’re less pondering about any individual seeing their clinical files. Deem me, I can cease a considerably greater job of decoding each one amongst these clinical files than decoding their genome on the novel time.

What retains you up at evening?

Inexperienced: I in point of fact bear wide concerns spherical equity, and spherical exacerbating health disparities. We couldn’t be excellent nonetheless one amongst the wrestle cries of the Institute is making genomics mainstream and equitable in treatment. We build now not wish to excellent be mainstream for those that’ve gone to Johns Hopkins or those that win their clinical care at Washington University, nonetheless I mediate relating to the general nooks and crannies of the clinical ecosystem.

Some other one amongst our greatest priorities is to diversify our team. I mean every facet of the genomics team, from a science communicator, to a leader, to a doctor, to a scientist, to a nurse, to a pharmacist — excellent all of it, attributable to we want our entire tent of folk touching genomics to repeat society. In genomics, it be in particular foremost attributable to we excellent build now not mediate we are going to bear interaction the communities and convince everyone to enjoy with genomics as segment of their clinical care except the other folks who they’re talking to resemble them more.

And on the other facet, what makes you angry to pass to work every morning?

Inexperienced: I’m surrounded by terrific folk and I have faith in what we’re doing is changing the world. So I mediate that makes a wide distinction to be with other folks that in point of fact are dedicated and are desirous about what we’re doing.

I hitched my wagon at a in point of fact early stage in my career, with this remarkably vague idea that genomics could well sooner or later trade the practice of treatment. And I guarantee then you definately — which could well were 1988 — or when the Human Genome Project ended twenty years ago, in 2003, I in point of fact did not have faith in I’d seek the fruits of it affecting treatment in any valid scheme in my lifetime. No longer handiest is it in my lifetime, it be whereas I’m aloof professionally active and I win to be assuredly within the pinnacle genomics region within the nation. Factual to bear this occur on my leer, it be ideally suited. It has reach fats circle from an incredibly vague idea of why I wish to cease any of this, to basically in point of fact feel admire I’ve moved the needle.

Thanks all as soon as more for talking with us!

Inexperienced: You’re welcome; reach relief any time!

Joyce Frieden oversees MedPage This present day’s Washington coverage, alongside with reports about Congress, the White Dwelling, the Supreme Courtroom, healthcare trade associations, and federal agencies. She has 35 years of trip covering health coverage. Apply

Health

“A Modern Awakening: How Gen Z Is Reshaping Spirituality”

Published

3 days ago

April 9, 2026

Ellora Cummins

Electric guitars and drums alongside a harmonium are placed at the center. Over the next hour, the rhythm pulsed like a club set, each chant building momentum the way a chorus does at a live concert. Around me, people swayed, clapped, and sang along, some with eyes closed, others smiling at one another. Yet, there were no chart-topping hits in the setlist. Instead, the evening unfolded through bhajans like Achyutam Keshavam and Raghupati Raghav Raja Ram.

Inside St Andrew’s Auditorium in Mumbai, the atmosphere felt like a curious fusion of part rave, part prayer. What might seem contradictory on paper felt surprisingly natural in practice: a distinctly Gen Z expression of spirituality that moves fluidly between kirtan gatherings, tarot circles, bhajan-inspired performances, and crystal pop-ups. According to Barkha Punjabi, a shamanic facilitator who works closely with younger clients, this generation is driven more by curiosity than convention. Rather than inheriting belief systems unquestioned, they are choosing to explore and interpret spirituality on their own terms.

For many young people today, spirituality is no longer confined to tradition or community expectations. Instead, it is approached almost like a creative pursuit, something to experiment with, adapt, and personalize. Punjabi notes that this shift reflects a broader desire to move beyond prescribed frameworks and discover meaning in ways that feel authentic and self-directed.

This evolution is particularly visible in the rising popularity of chant-led events. What once belonged to intimate, home-based gatherings is now finding space in ticketed venues and curated experiences. Performances by artists like Radhika Das, collectives such as Backstage Siblings, and initiatives like Kirtan Mumbai are drawing notably young audiences. These events offer something that feels both ancient and immediate, ritual reimagined through a contemporary lens.

For Meghna Siraj, co-creator of Kirtan Mumbai, this trend speaks to a deeper emotional landscape. Many young people, she explains, are navigating a sense of social, political, and personal. In that context, collective chanting becomes more than just a spiritual act; it becomes a grounding experience. When voices come together in unison, it creates a moment of stillness, a shared pause that fosters connection and belonging.

As these gatherings evolve, so too does their sound. Musicians are increasingly blending traditional kirtan with modern musical elements, creating an experience that feels immersive without losing its essence. As Baldev Maheshwari points out, this fusion does not necessarily dilute tradition when approached with care. Instead, it opens the door for those who might never step into a temple or attend a satsang, making spirituality more accessible and inclusive.

Not all expressions of this shift are as performative. In quieter settings, spirituality takes on more intimate forms through tarot readings, Reiki sessions, or curated crystal collections. These spaces offer a different kind of comfort: a sense of symbolism, reflection, and temporary grounding in an otherwise fast-moving world.

For individuals like Ishita Bangera, spirituality began as a response to overwhelm. Growing up amid constant digital engagement and societal pressure, practices like Reiki and tarot became tools for self-awareness and emotional balance. They provided not answers, but a framework for introspection, a way to reconnect with oneself in moments of disconnection.

This renewed interest in spirituality is perhaps unsurprising in the context of modern anxieties, climate uncertainty, economic pressures, and the relentless visibility of digital life. As Punjabi observes, many who turn to spirituality have already achieved conventional markers of success, only to find them insufficient. What they seek instead is a deeper, more enduring sense of fulfillment.

At the same time, spirituality today exists alongside logic and science rather than in opposition to them. Supported by the rise of therapy culture, mindfulness practices, and mental health awareness, it has become part of a broader ecosystem of self-regulation and well-being.

The satsangs of previous generations and today’s bhajan-infused gatherings may differ in form, sound, and setting. Yet, at their core, they share the same intent: to cultivate attention, surrender, and a sense of belonging. While the aesthetics have evolved, the underlying impulse remains unchanged: the timeless human desire to seek meaning.

Health

Blockchain Unlocked: Revolutionizing Modern Marketing with Unbreakable Trust and Transparency

Published

4 days ago

April 8, 2026

Ellora Cummins

Businesswoman use a smartphone connecting to blockchain global networking, Token money bank bitcoin, cloud data network connect, cyber security binary coded, Blockchain technology concept.

How Blockchain is Transforming Marketing in 2026: Real Impact, Persistent Challenges, and Actionable Steps

Blockchain, once primarily known for enabling secure digital payments, has evolved into a powerful tool for modern marketing. In 2026, amid stricter privacy regulations, the decline of third-party cookies, and rising concerns over data ownership, brands are turning to blockchain to build transparency, trust, and efficiency in their campaigns.

What is Blockchain and Why Does It Matter?

Blockchain is a decentralized digital ledger that records information across thousands of computers worldwide. Unlike traditional centralized databases, it operates as an immutable chain of blocks. Once data is added and verified by the network through consensus, it becomes nearly impossible to alter without majority agreement. This tamper-proof nature makes it ideal for verifying transactions, identities, and interactions of critical assets in today’s skeptical digital landscape.

Blockchain’s Disruption in Digital Marketing

The biggest shift lies in moving away from centralized data giants like Google, Meta, and Amazon toward privacy-first, decentralized ecosystems. With global regulations tightening and AI-generated deepfakes proliferating, blockchain offers verifiable, consent-driven data sharing that respects user privacy while enabling smarter targeting.

Real-World Example:

Imagine a customer buys running shoes from a retailer. With explicit opt-in consent, the purchase is recorded on a shared blockchain network. Partner brands can instantly access verified insights without seeing raw personal data and deliver relevant offers like fitness apparel or local race events across platforms. This reduces wasted ad spend and improves relevance in real time.

Greater Ad Transparency and Reduced Fraud

Ad fraud remains a massive drain on budgets, with estimates suggesting 25-30% of digital ad impressions wasted on bots. Blockchain addresses this by timestamping and recording every ad impression as a unique, verifiable transaction on an immutable ledger. Through consensus mechanisms, the network confirms genuine human interactions, making it extremely difficult to inflate numbers or create fake traffic.

Brands no longer need to blindly trust third party platforms. Instead, they gain full visibility into where ads appear and how audiences truly engage, ensuring every dollar delivers real value.

Eliminating Redundant and Annoying Ads

Blockchain also solves the frustration of repetitive advertising. When a customer completes a purchase on one platform, the updated record instantly syncs across participating networks. Other sites and partners automatically stop serving the same ad, reducing annoyance and cutting unnecessary costs for advertisers.

This creates a more efficient customer journey, allowing marketers to focus on meaningful frequency and better lead generation rather than over-exposure.

Real-World Impact

Major brands are already seeing results. Unilever, in partnership with IBM, has piloted blockchain solutions to enhance transparency in the advertising supply chain, helping verify genuine impressions and significantly reduce fraud. As interoperability between blockchains improves and industry standards mature, more success stories are emerging.

Challenges Ahead

Despite progress, challenges persist. Scalability issues, high implementation costs, complex integration across different blockchain networks, and evolving regulatory frameworks can slow adoption. Data privacy concerns and the need for widespread industry collaboration also remain hurdles.

Actionable Steps for Marketers

Start Small: Pilot blockchain-based ad verification or loyalty programs with a single campaign or partner network.
Prioritize Consent: Build opt-in mechanisms that give users control over their data. Transparency builds long-term trust.
Focus on Partnerships: Join or explore industry consortia (such as those involving IBM or Mediaocean) for shared blockchain infrastructure.
Measure ROI Clearly: Track metrics like reduced fraud rates, improved engagement quality, and lower redundant spend.
Stay Educated: Monitor interoperability advancements and regulatory updates in 2026 to scale effectively.

Blockchain is no longer future hype; it is delivering measurable transparency and efficiency today. Marketers who embrace it strategically will gain a competitive edge in building authentic customer relationships while optimizing budgets in an increasingly privacy-conscious world.

Health

“Hepatitis Warning: How to Stop Infections from Turning into Chronic Liver Disease”

Published

5 days ago

April 7, 2026

Ellora Cummins

Protect Your Liver: How Hepatitis Can Lead to Chronic Liver Disease and Simple Preventive Tips

Your liver is one of the hardest-working organs in your body, performing over 500 vital functions every day. Yet, it often goes unnoticed until something goes wrong. The truth is, you don’t get a second liver. Once it fails, the consequences can be life-threatening.

Liver diseases range from mild and reversible conditions to severe, terminal ones like chronic liver cirrhosis. Long-term inflammation caused by hepatitis viruses can silently damage liver cells, leading to scarring, hardening, and swelling. Over time, this impairs the liver’s ability to function, increasing the risk of serious complications.

Hepatitis infections, caused by different viruses (mainly A, B, and C), trigger inflammation in the liver. While some cases resolve on their own, others become chronic and progress to dangerous liver diseases. The good news? Many hepatitis infections and the resulting liver damage are preventable with simple lifestyle changes and precautions.

Here are six essential preventive tips to lower your risk of hepatitis and protect your liver health:

Maintain a Healthy Weight

Obesity is a major risk factor for fatty liver disease, which can lead to cirrhosis. Adopt a balanced, low-fat diet rich in fruits, vegetables, lean proteins, and whole grains. Regular physical activity helps reduce fat buildup in the liver and supports overall liver function.

Limit Alcohol Consumption

Excessive drinking is extremely harmful to the liver. Alcohol causes inflammation and swelling, speeds up liver damage, and significantly raises the risk of cirrhosis. If you drink, do so in moderation — or better yet, avoid it completely if you already have liver concerns.

Be Careful with Medications

Many common medicines, including paracetamol (acetaminophen), aspirin, and ibuprofen (NSAIDs), can harm the liver when taken excessively or long-term. Always follow recommended doses. If you have existing liver issues, consult your doctor before taking supplements, herbal remedies, or high doses of vitamin A and iron, as some can be hepatotoxic.

Get Vaccinated

Safe and effective vaccines are available for Hepatitis A and Hepatitis B. Completing the full vaccination course is one of the best ways to prevent these viral infections and protect your liver from long-term damage. Speak to your doctor about getting vaccinated, especially if you are at higher risk.

Practice Good Personal Hygiene

Hepatitis A and E spread mainly through contaminated food and water. Wash your hands thoroughly with soap and water before eating and after using the toilet. Drink clean, safe water and avoid raw or undercooked food, especially while travelling. Practice safe sex, never share needles or personal items (like razors or toothbrushes), and avoid direct contact with an infected person’s blood or bodily fluids.

Eat a Liver-Friendly Diet

Support your liver by choosing nutrient-rich foods. Focus on fresh fruits and vegetables, whole grains, and lean protein sources. Reduce intake of processed foods, fried items, and excessive fats. Eating smaller, balanced meals throughout the day can also ease the liver’s workload.

By adopting these habits, you can significantly reduce your risk of hepatitis infections and prevent chronic liver disease. Remember, early prevention is far better than dealing with advanced liver complications later.

Health

Bangladesh’s Measles Surge Raises Alarm: Are India’s Border States at Risk?

Published

5 days ago

April 7, 2026

Ellora Cummins

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With over 100 deaths reported, the outbreak highlights gaps in vaccination, and the risks of cross-border spread

A deadly measles outbreak in Bangladesh is raising fresh concerns across South Asia, especially in neighbouring India. With the virus known for its extreme contagiousness, health experts warn that no border is strong enough to stop its spread, particularly in communities with low vaccination coverage.

Bangladesh has reported 118 deaths, most of them children, since mid-March. According to the Directorate General of Health Services (DGHS), more than 2,000 suspected cases are currently being treated in hospitals. Alarmingly, five deaths were recorded within just a 24-hour window, underscoring the rapid spread of the disease. Health experts in Bangladesh have linked the surge to disruptions in vaccination programs. Benazir Ahmed, a former director of disease control at DGHS, pointed to the cancellation of a key immunisation initiative, which created a vaccine shortage and left many children vulnerable. The situation is particularly concerning as the country had set a goal to eliminate measles and rubella by 2026.

Measles is one of the most contagious viral diseases, capable of spreading through air and direct contact. According to global health authorities, even a single infected individual can trigger an outbreak in under-vaccinated populations. Given the movement of people across borders, through travel, migration, and trade, the risk of transmission cannot be ignored.

Experts say India is well-prepared, but vigilance, vaccination, and hygiene remain critical to staying safe.

However, experts believe India is in a relatively strong position. Recent data shows that measles-rubella (MR) vaccination coverage in India stands above 90% for both doses. This high coverage has significantly reduced cases, with a 73% drop in measles infections recorded in 2024 compared to the previous year. Paediatrician Dr. Sanjeev Bagai notes that India’s long-standing immunisation efforts have built a solid defence. “The country has achieved a level of herd immunity, which offers protection at the community level,” he explains. Still, he cautions that risks remain due to global and regional movement, adding that air travel and migration can contribute to the spread, especially from regions with weaker healthcare systems. Despite this, experts stress that there is no immediate cause for panic, provided vigilance is maintained.

Protecting yourself and your family starts with vaccination. The MMR vaccine is highly effective, offering up to 97% lifelong immunity after two doses. Children should receive their first dose between 12–15 months and the second between 4–6 years, while unvaccinated adults should also consider getting immunised. Alongside vaccination, basic hygiene practices such as frequent handwashing, proper respiratory etiquette, and maintaining clean, well-ventilated spaces can significantly reduce the risk of infection. During outbreaks, it is advisable to avoid crowded or poorly ventilated areas and seek medical advice promptly if symptoms like fever, rash, or respiratory issues appear.

As Bangladesh battles a growing health crisis, the situation serves as a timely reminder that in an interconnected world, infectious diseases can travel fast, but with strong vaccination coverage and timely precautions, their impact can be contained.

Health

“Want Better Health? Start Adding These 8 Anti-Inflammatory Spices to Your Daily Meals”

Published

6 days ago

April 6, 2026

Ellora Cummins

Add These 8 Powerful Anti-Inflammatory Spices to Your Meals and Transform Your Health

Anti-inflammatory eating doesn’t require a complete diet overhaul. In most Indian households, these potent spices have been used for generations in everyday meals from dals and subzis to curries, teas, and traditional home remedies. The real change comes from being more mindful and intentional about incorporating them regularly across your dishes. This simple habit offers a practical and sustainable way to support your body, especially in managing everyday low-grade inflammation caused by stress, poor sleep, processed foods, pollution, and fluctuating blood sugar levels.

What makes these spices even more valuable is that many are among the highest natural sources of antioxidants. They help the body fight oxidative stress, a key driver of chronic inflammation, premature ageing, and several lifestyle-related diseases.

The Benefits of Anti-Inflammatory Spices

“Inflammation increases when the body is constantly under stress from an unbalanced diet, lack of sleep, pollution, or repeated blood sugar spikes,” explains Aken Sanghavi, founder of CNTH (Apeiro Biosciences). “Over time, this leads to oxidative stress and cellular damage. Spices like turmeric, cinnamon, cloves, and ginger contain powerful bioactive compounds that help regulate these processes. They don’t eliminate inflammation entirely, but they prevent it from staying elevated for too long.”

This internal balance also shows visible results on the skin. “Any skin condition with an inflammatory root, such as acne, eczema, psoriasis, or pigmentation issues, can significantly improve when systemic inflammation is kept in check,” adds Sanghavi.

Here are eight of the most effective anti-inflammatory and antioxidant-rich spices commonly found in Indian kitchens:

Ranked among the highest antioxidant foods globally, cloves are rich in eugenol. They help reduce inflammation, combat oxidative stress, and support cellular health. Just a small pinch delivers powerful benefits.
Cinnamon is loaded with polyphenols, which help lower inflammation, stabilise blood sugar, and offer antibacterial properties that protect the body from long-term cellular damage.
Turmeric The crown jewel of Indian spices, turmeric’s curcumin is a potent anti-inflammatory and antioxidant compound known for neutralising harmful free radicals.
Ginger: Thanks to gingerol, ginger provides strong anti-inflammatory and antioxidant effects. It aids digestion, helps the body respond better to stress, and soothes internal inflammation.
Garlic Its sulfur compounds, especially allicin, reduce inflammation, boost immunity, support heart health, and fight oxidative damage.
Fenugreek is rich in flavonoids and polyphenols; fenugreek seeds offer excellent antioxidant and anti-inflammatory benefits while supporting healthy blood sugar levels.
Cumin is a kitchen staple with strong antioxidant properties. Cumin aids digestion and helps combat daily inflammation.
Black Pepper Beyond adding flavour, black pepper contains piperine, which has its own anti-inflammatory and antioxidant effects. Most importantly, it dramatically enhances the absorption of curcumin from turmeric.

Simple Daily Rules to Maximise Benefits

Always combine turmeric with black pepper for better absorption.
Use ginger and garlic as a cooking base.
Add high-antioxidant spices like cloves and cinnamon in small amounts.
Finish meals with digestive spices such as cumin or fennel.

“The real benefit comes from consistent, daily use as part of a balanced diet,” says Sanghavi. “When combined regularly, these spices help the body manage inflammation and daily wear and tear more effectively.”

At the same time, moderation is crucial. “These are bioactive compounds, not neutral ingredients,” cautions Atul Rajani, founder and chief innovation officer at Be. “In excess, especially in concentrated forms, they may irritate the gut or create imbalances.”

Rajani recommends a practical approach: “Start gradually, listen to your body, and keep portions reasonable. Even common spices like turmeric or chilli can trigger flare-ups in sensitive individuals if overused. Small, consistent habits such as adding a pinch of turmeric with black pepper to your daily dal or rice are what truly create lasting change.”

Health

“7 Rich Woody & Smoky Women’s Fragrances for a Darker Twist”

Published

1 week ago

April 3, 2026

Ellora Cummins

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Some women have moved on from smelling like a flower garden. They no longer want soft rose, peony, or overly sweet scents that fill a room before they do. Instead, they seek fragrances with depth and attitude, woody, smoky, spicy, and sometimes lightly leathery. These scents feel like putting on a sharp, tailored blazer or walking into a dimly lit bar: confident, mysterious, and quietly rebellious.

David Benedek, founder of BDK Parfums, doesn’t believe in strictly dividing fragrances by gender. “All aromas in perfumery are genderless,” he says. “A man can love florals, just as a woman can love woody and smoky profiles. It’s about what feels right for you.”

Woody and smoky notes offer a unique strength on the skin. Sandalwood, cedarwood, and vetiver bring a grounded, quietly luxurious feel that lasts. Smoky accents tobacco, incense, guaiac wood, or dark amber add warmth, intensity, and intrigue. Even oud, when masterfully blended, can range from bold and animalic to soft and sensual.

These fragrances are also surprisingly versatile. Clean, lighter woody scents work beautifully during the day for a polished, sophisticated presence. Richer, smokier compositions come alive at night, ideal for dinners, dates, weddings, or any occasion where you want your perfume to feel like a statement.

If you’re tired of traditional florals and ready for something with real character and backbone, here are seven exceptional woody and smoky women’s fragrances:

1. Guerlain Tabac Sahara – ₹20,350 Smoky tobacco meets juicy raspberry and warm ambergris. Rich, spiced, and nocturnal like berries smoked over glowing embers.

2. Tom Ford Soleil Neige – ₹12,900 Cool and refined with a dark edge. Bright bergamot and white florals are deepened by resinous labdanum, benzoin, and musk for an ambery, luxurious twist.

3. Kilian Paris Angels’ Share On The Rocks – ₹21,500 Boozy cognac, bitter orange, cinnamon, myrrh, and oak deliver a warm, ambered depth with a crisp, chilled edge. Intoxicating and bold.

4. Ajmal Perfumes Strings Of Oud – ₹8,000 Cardamom, wormwood, and pepper open into layers of incense, tobacco, cedar, and bourbon vanilla. A plush, smoky oriental-woody delight.

5. BDK Parfums Nuit De Sable – ₹21,000 Dry and seductive. Cardamom, nutmeg, cumin, and hot sand blend with Turkish rose and a warm base of sandalwood, tonka, and ambroxan for spiced, desert warmth.

6. Marc Jacobs Fragrances Perfect Absolute – ₹12,995 Caramelised fig and jasmine absolu rest on a rich amber base, creating a lush, sensual, and grounded warmth.

7. Jo Malone London Amber Labdanum – ₹17,900 Bitter orange lifts the top while labdanum, roasted oak, vanilla, and amber build a deep, resinous, smoky base. Perfect evening elegance.

Health

Inside the $550 Million Deal Fueling America’s Data Center Gold Rush

Published

2 weeks ago

April 1, 2026

Ellora Cummins

A Hyperscaler Partnership That Signals a Massive Shift in Digital Infrastructure

What if the next big tech revolution wasn’t just about chips, code, or cloud, but about where people sleep, eat, and live? As artificial intelligence and cloud computing explode at an unprecedented pace, a surprising player is stepping into the spotlight. Target Hospitality Corp. has just landed a staggering $550 million contract, not to build servers, but to build the human backbone behind them. And in doing so, it may have unlocked one of the most overlooked opportunities in the booming data center economy.

The Texas-based company has signed a multi-year lease and services agreement with a top-five hyperscaler, one of the global giants driving the digital age, to support a sprawling data center campus in North Texas. The deal guarantees over $550 million in revenue through early 2031, with options extending to 2035 and the potential to generate an additional $20–$40 million annually once the facility reaches full capacity.

This isn’t just a contract, it’s a clear signal that the data center boom is entering a new phase, where infrastructure goes far beyond machines.

From Workforce Housing to 4,000-Person Smart Communities

At the core of this deal lies an ambitious vision: building an entire purpose-designed community to house nearly 4,000 workers. But this isn’t your typical accommodation setup. It’s a fully integrated, self-sustaining ecosystem built to support the demanding needs of large-scale, remote digital infrastructure projects.

Construction is already underway, with first occupancy expected by the third quarter of 2026 and full completion slated for mid-2027. To deliver this, Target Hospitality plans to invest between $115 million and $125 million, with the majority of capital deployed in 2026.

What makes this project stand out is its all-encompassing approach. Beyond housing, the company will provide food services, logistics, security, laundry, and recreational facilities, essentially creating a mini-city tailored for a modern, mobile workforce powering the digital economy.

This marks a major strategic shift for Target Hospitality, which has traditionally catered to the energy and government sectors. Now, it is rapidly repositioning itself at the heart of the tech infrastructure boom. As hyperscalers expand aggressively to keep up with AI and cloud demand, the need for scalable workforce solutions is skyrocketing, and Target Hospitality is capitalizing on that gap.

The financial upside is already becoming evident. The company has raised its 2026 revenue forecast to between $360 million and $370 million, with adjusted EBITDA projected at $70 million to $80 million. By mid-2027, it expects annual revenues to exceed $500 million, driven largely by this landmark deal.

Investors are paying close attention. The company’s stock has delivered strong returns over the past year, reflecting growing confidence in its evolving business model and long-term growth potential.

In many ways, this deal captures a larger transformation underway. The digital economy isn’t just being built in data centers, it’s being built around them. And as the demand for data surges, companies like Target Hospitality are proving that even in a tech-driven world, people, and the infrastructure that supports them, remain at the center of it all.

Health

Escape to Chefchaouen: A Magical Day in Morocco’s Blue City

Published

2 weeks ago

April 1, 2026

Ellora Cummins

Chefchaouen: Morocco’s Famous Blue City – The Ultimate Day Trip Guide

Tucked into the Rif Mountains of northern Morocco, Chefchaouen is one of the country’s most iconic destinations. Known worldwide as “The Blue City,” this charming mountain town features streets, buildings, and alleyways painted in every shade of blue from soft sky tones to deep cobalt.

You can easily visit Chefchaouen as a day trip from Fes or Tangier. While many travelers choose to stay overnight, a well-planned day trip is more than enough to experience its highlights.

This guide covers everything you need to know: how to reach the Blue City, what to see, best photo spots, and honest travel advice.

Best Way to Visit Chefchaouen

I visited Chefchaouen on a day trip from Fes and highly recommend doing the same. The most convenient and hassle-free option is joining an organized tour.

Recommended Tour:

I booked my day trip through GetYourGuide for just $26 USD. The package included comfortable minivan transportation, a local guide, and about 4 hours to explore the city. It was excellent value and very well organized.

Book Here: Chefchaouen Day Trip from Fes or Tangier

How to Get to Chefchaouen

From Fes

By Public Bus: The journey takes around 4 hours. Buses are a safe, comfortable, and affordable mode of transportation, with multiple daily departures operated by CTM and other companies.
Private Driver: Faster and more comfortable than the bus. Ideal if you’re traveling with friends and can split the cost. You can arrange this through your hotel or book online.

From Tangier

Tangier is much closer the drive takes only about 2.5 hours.

Public buses (CTM) run several times a day and are the cheapest option.
Private transfers and shared day tours are also widely available.

What to Expect in Chefchaouen

Chefchaouen is compact and very walkable. Most visitors enter through Bab El Ain, the main gate of the medina. The town has a relaxed and peaceful atmosphere compared to the busier Moroccan cities of Marrakech or Fes.

Be prepared for some uphill walking and stairs, as many alleys are sloped. If you’re traveling with luggage from the bus station, a short taxi ride to the medina gate is recommended.

While generally safe and friendly, you may encounter a few local touts. The town is picturesque but not spotless you’ll see stray cats and dogs, and some areas could use better maintenance.

Best Photo Spots in Chefchaouen

These are the most Instagrammable locations:

Alley of Colored Pots (Derb El Assri): The most famous blue alley, decorated with hanging pots and vibrant colors.
Orange Juice Shop: A charming spot with plastic oranges hanging overhead. Great for photos and fresh juice.
Solid Blue Alley: Pure blue walls and doors perfect for clean, minimalist shots.
Place El Haouta: A scenic square with a fountain and beautiful mountain views.
Mural Street: Quirky street art featuring Greek Santorini-style murals.
Magic Lamp House of Aladdin: Excellent rooftop views over the blue medina.

Other Attractions Worth Seeing

The Kasbah: The historic fortress built in 1471. Climb the tower for panoramic views of the town.
Ras El Maa Waterfall: A short uphill walk from the medina. A peaceful spot to relax.
Bouzafer Mosque (Spanish Mosque): Offers one of the best viewpoints over Chefchaouen. Many tours stop here for photos.

How Long Should You Stay?

Four hours in Chefchaouen is usually sufficient to explore the medina, take photos, and enjoy a meal. While some people choose to overnight here, I personally found a day trip perfectly adequate. From Fes it’s a long day (8+ hours of driving), but from Tangier you’ll have more time to enjoy the town.

Is Chefchaouen Worth Visiting?

Yes — but with realistic expectations.

Chefchaouen is beautiful and unique, but it’s not as pristine or magical as it appears on social media. The blue alleys are lovely, yet the town has stray animals, some trash, and isn’t as polished as Santorini. Lower your expectations slightly, and you’ll have a wonderful time wandering its colorful streets.

Why Is Chefchaouen Painted Blue?

The exact reason remains a mystery. Popular theories suggest the blue color repels mosquitoes, symbolizes the sky and sea, or was painted to attract visitors. Whatever the reason, it has certainly worked Chefchaouen has become one of Morocco’s most photographed destinations.

Fashion

The Real Story of Fashion in Northeast India Goes Far Beyond Beauty Pageants and Thrift Clichés

Published

2 weeks ago

March 26, 2026

Ellora Cummins

For years, the narrative around fashion in Northeast India has remained frustratingly narrow. The region’s style has often been reduced to three tired clichés: cultural shows, beauty pageants, and the romanticised myth of thrift shopping. While none are entirely untrue, they fail to capture the complete picture.

The first Aizawl Design Project proved just how outdated these assumptions have become. Its debut public event, the Zoram Fashion Showcase, held on March 10 at LPS Arena in Aizawl, started from a sharper premise: the people of the hills must author their own cultural narrative. For decades, Mizoram’s crafts and visual language have been romanticised and interpreted largely through an external gaze.

The collections, styled by Aizawl-born stylist James Lalthanzuala, featured three distinct Mizo designers, Hannah Khiangte, Lapâr, and Escape Engmoia each working with the indigenous Zo puan textile of Mizoram and neighbouring regions. Held in Aizawl, the showcase recalibrated what fashion from Northeast India could look like when creatives move beyond traditional expectations of how indigenous textiles should be worn and celebrated.

The event was conceived and curated by Lal Moya, a Mizo creative based in Washington DC. “As a Mizo creative, I have always believed our designers deserve the same level of staging and presentation seen anywhere in the world,” he said. “The talent has always been here. What we needed was the platform and the courage to present it properly.”

For decades, fashion from the Northeast has shouldered the burden of representation. Clothes were expected to signify tribe, tradition, identity, or solidarity, while experimentation and self-expression often took a backseat. The Aizawl Design Project instead highlighted a new generation of creatives who no longer feel bound by that obligation.

These designers are treating indigenous textiles as living, adaptable materials rather than frozen artefacts. “My collection draws from the idea of Khawtlang Lunglen,” says Hannah Khiangte. “We Zo descendants are melancholic people the evidence is all over our songs and literature.” Her punk-infused take on yearning featured frayed hems, sharp cuffs, stiff tailoring, and rose appliqués in warm sienna and canary tones, evoking the afterglow of a fading summer day over Aizawl’s hills. Founded in 2013, her label is now sought after by top stylists like Rhea Kapoor, with the aim of taking Mizo weaves to a global stage.

Lapâr, established in 2017 by Patricia Zadeng (a National Institute of Design graduate with experience at Rahul Mishra and Maku Textiles), champions local women weavers through back-strap loin loom techniques. Her collection explored colonial influences from the arrival of missionaries in the late 19th century, reimagining traditional drapes in dandy forms wraparound skirts paired with shirts and ties, and boxy blouses reworked with matching trousers.

Escape Engmoia, whose name reflects fashion as an escape from everyday life, drew inspiration directly from Mizoram’s landscape. Having represented Indian textiles internationally, his collection translated the region’s hairpin bends and hilly slopes into asymmetric cuts, woven floral patterns, and generous layering making each look feel like Mizoram itself.

This showcase did not erase cultural heritage. Instead, it placed Zo puan and Northeast Indian fashion firmly within the broader global conversation. Indigenous textiles and techniques became part of a wider creative toolkit rather than mere spectacle for traditional parades or pageants.

The most powerful shift is clear: fashion from the Northeast is no longer seeking validation through cultural tokens. Designers are building their own communities, creating their own platforms, and shaping their own visual identities. The region’s fashion scene has always brimmed with unbridled style. Now, it is finally gaining the space to experiment, evolve, and exist beyond narrow scripts.

Health

The Rise of Micro-Entrepreneurs: How Small Businesses Are Winning in a Big Market

Published

3 weeks ago

March 25, 2026

Ellora Cummins

What if the next big business success story isn’t a billion-dollar startup, but a one-person brand run entirely from a smartphone?

Across the world, a quiet revolution is taking shape. Micro-entrepreneurs, individuals or very small teams building lean, focused businesses, are challenging traditional ideas of scale and success. They may not have massive budgets or corporate infrastructure, but they are proving that in today’s digital economy, small can be incredibly powerful.

Breaking Barriers: How Technology Is Empowering the Smallest Players

Not long ago, launching a business required significant capital, physical infrastructure, and access to networks that were often out of reach for many. Today, the rules have changed dramatically. With just a laptop or a phone, entrepreneurs can build brands, reach global audiences, and generate revenue.

Social media platforms have evolved into full-fledged marketplaces. Payment systems have simplified transactions, and logistics networks have made delivery faster and more reliable than ever. What was once exclusive to large corporations is now accessible to individuals with determination and a clear idea.

But access to tools is only part of the story.

Micro-entrepreneurs are thriving because they know how to use these tools differently. They don’t just sell products, they build narratives. Whether it’s a handmade clothing label, a niche consulting service, or a homegrown food brand, these businesses are rooted in authenticity. They communicate directly with their customers, respond quickly, and create a sense of belonging that larger brands often struggle to replicate.

In a world saturated with choices, this personal touch stands out.

The Power of Connection and Agility in a Fast-Moving Market

One of the biggest advantages micro-entrepreneurs have is their ability to move fast. Without layers of management or lengthy approval processes, they can test ideas, adapt to trends, and refine their offerings almost instantly.

This agility allows them to stay ahead in a market that is constantly evolving. While larger companies may take months to respond to a shift in consumer behavior, micro-entrepreneurs can pivot in days, or even hours. That responsiveness creates relevance, and relevance drives growth.

Equally important is the emotional connection they build with their audience. Today’s consumers are not just buying products, they are buying stories, values, and experiences. Supporting a small business often feels more meaningful, more human. It’s not just a transaction; it’s a connection.

This shift in consumer mindset has created a powerful advantage for micro-entrepreneurs. People are increasingly drawn to brands that feel real, transparent, and purpose-driven. And that’s exactly what small businesses excel at delivering.

Of course, the journey isn’t without its challenges. Limited resources, financial uncertainty, and the pressure of managing every aspect of the business can be demanding. Yet, for many, the rewards go beyond profits. The ability to create, control, and grow something independently is a compelling motivator.

The rise of micro-entrepreneurs reflects a deeper transformation in how success is defined. It’s no longer just about size or scale, it’s about impact, flexibility, and authenticity.

So the next time you come across a small brand online, pause for a moment. Behind it could be a single individual redefining the rules of business, and quietly proving that even in a big market, small can win.