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Blocking off a tiny RNA could well forestall age-connected bone and muscle loss, inflammation

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Blocking off a tiny RNA could well forestall age-connected bone and muscle loss, inflammation
Blocking off a tiny RNA could well forestall age-connected bone and muscle loss, inflammation

Sadanand Fulzele, DVM, PhD, and first author and postdoctoral fellow Sagar Vyavahare, PhD. Credit rating: Michael Holahan, Augusta University

Inhibiting a tiny RNA whose ranges enormously enlarge with age, along with concerns admire weaker bones and sagging muscles, will be one draw to withhold our bodies more youthful and healthy, scientists content.

MicroRNAs aid control gene expression and consequently the feature of our cells, and loads of alternative, collectively with one known as microRNA-141-3p, had been implicated in the ills of growing outdated, admire growing ranges of with out doubt unfavorable power inflammation and that scared muscle tissue.

“When we age in all these concerns admire power inflammation, muscle loss, bone loss, this microRNA is elevated,” says Sadanand Fulzele, DVM, Ph.D., growing outdated researcher in the Division of Pills on the Medical College of Georgia at Augusta University. “We wanted to suppress it.”

In what appears to be like to be the principle seek of its kind, Fulzele and his colleagues faded an inhibitor he had specifically designed to dam microRNA-141-3p in worn mice. These styles of engineered molecules are known as antagomirs, and while on the 2d restricted to research, could well one day occupy therapeutic fee for patients, says Fulzele, corresponding author of the seek in the journal Aging and Illness.

The mice, who would equate to folks in their 60s, were treated for 3 months with twice-weekly subcutaneous injections of this antagomir, a regimen that will be with out problems adapted for folks.

The scientists then regarded at changes that took place in the blood, the spleen whose tasks consist of regulating ranges of infection-preventing white blood cells, in addition to the bone and muscle. They realized a more youthful profile in all places they regarded.

In the spleen, as an illustration, they observed more inflammation-cutting again immune cells known as macrophages (M2) rather than their inflammation-promoting counterpart (M1). M2s furthermore had been reported to bolster tissue restore. The blood had lower ranges of inflammation-promoting proteins known as cytokines, and the microstructure of the bone used to be more stable and muscle fiber size used to be bigger.

They realized that microRNA-141-3p regulates expression of AUF1, a “appropriate” gene whose many jobs consist of regulating the soundness of messenger RNA, which plays a position in the proteins DNA ultimately makes. AUF1 helps defend youthful folks from making so many proinflammatory merchandise admire IL-6 which make a contribution to power, unfavorable inflammation. It does the equivalent for cell senescence when cells change into less ready to feature on the full and divide nonetheless in most cases don’t die. Elevated ranges of microRNA-141-3p mean less of the protective AUF1 and blocking off the microRNA enabled increased ranges and consequently less inflammation and senescence.

Fulzele notes that admire with all the pieces else in the physique, the attain of microRNA-141-3p has to pause with its degree of expression and in growing outdated its high. Their most modern findings point toward cutting again its expression as a that you are going to be ready to imagine technique to toughen immune, bone and muscle health with age, Fulzele says.

Stages of inflammation and oxidative stress are an indicator of total health at any age. Persistent inflammation and power oxidative stress are hallmarks of an growing outdated physique and annoying avid gamers in the harmful changes that could well pause up.

With age, the restore/replacement potential of cells is known to lower in sing that, as an illustration, bone loss begins to outpace new bone formation. Meanwhile inflammation, very crucial to healing nonetheless harmful at power, high ranges, creeps upward. Resulting concerns can vary from growing physical frailty to an increased incidence of illnesses admire most cancers, cardiovascular disease and dementia.

Fulzele notes that his research is geared toward discovering ways to forestall ruin, rather than making an are attempting to revive a healthy customary. Some of his next steps consist of taking a gape at how blocking off the microRNA impacts other age-connected concerns admire cognition and giving the microRNA-141-3p-explicit antagomir for a protracted timeframe. He popular they failed to name any overt side outcomes over the three months of the seek.

Fulzele and his colleagues reported in 2018 proof that with age, expression of microRNA-141-3p went up while the important thing signaling molecule stromal cell derived element 1, or SDF-1, that helps stem cells catch healthy bone and muscle, goes down in the mesenchymal stem cells which is liable to be to blame for making bone and muscle in addition to fats. SDF-1 helps control the differentiation into totally different cell kinds. In both human and mouse mesenchymal stem cells the scientists realized ranges of microRNA-141-3p were low in youthful cells and tripled or bigger in older cells. Stages of SDF-1 in these cells were straight reverse. With age, mesenchymal stem cells furthermore catch more fats, rather than bone or muscle, which they are inclined to pause attributable to fats’s less difficult to catch.

Extra info:
Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Feeble Mice, Aging and Illness (2023). DOI: 10.14336/AD.2023.0310-1. www.aginganddisease.org/EN/10.14336/AD.2023.0310-1

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7 Types of Anxiety Disorders and How to Identify Yours

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types of anxiety disorders

Types of anxiety disorders affect nearly one in five Americans today, but many people don’t even realize which one they’re living with. Anxiety isn’t just nervousness before a big presentation or worrying about tomorrow’s deadline. It can take on many forms, some loud and visible, others quiet and consuming.

For millions across the U.S., anxiety is not an occasional visitor, it’s a daily weight. The struggle is often silent, internal, and misunderstood. Many chalk it up to being a “worrier,” an “overthinker,” or “just sensitive.” But what they’re experiencing could actually fall under one of the diagnosable types of anxiety disorders, and the difference between knowing and not knowing can be life-changing.

In a world that’s constantly pushing us to be faster, better, and more connected, anxiety can become a quiet epidemic. Let’s break down the 7 most common types of anxiety disorders, how they manifest, and what to look out for when deciding to seek help.

1. Generalized Anxiety – A Common Type of Anxiety Disorder

This is perhaps the most widespread and sneaky form of anxiety. Generalized Anxiety Disorder (GAD) shows up as chronic, excessive worry over day-to-day life, your job, health, money, or even the weather. It’s not tied to any one event; it’s a baseline state of mental unrest.

What makes GAD hard to spot is that the thoughts often feel logical. But if worry has become your default setting, if your mind is never at rest, it’s likely more than just stress. You may find it’s interfering with your ability to concentrate, sleep, or make decisions.

2. Panic Disorder – One of the Intense Types of Anxiety Disorders

A panic attack feels like your body is under attack. It can come on suddenly, triggering intense fear, shortness of breath, chest pain, dizziness, and a sense of losing control. People with panic disorder don’t just fear the attack, they fear the fear itself.

Because of this, they may avoid places, people, or activities that could “trigger” the next episode. Over time, this builds into a cycle that limits their freedom and social life. The type of anxiety disorder that is panic-based is highly disruptive, but also highly treatable.

types of anxiety disorders

3. Social Anxiety Disorder – When Connection Feels Like Danger

Social anxiety is more than shyness, it’s a paralyzing fear of being judged, embarrassed, or rejected in social settings. This fear often triggers sweating, blushing, trembling, or even nausea during simple social interactions.

This type of anxiety disorder can make it difficult to speak up in meetings, go on dates, or even make small talk. Ironically, those who suffer from social anxiety are often highly empathetic and perceptive, they just battle an inner voice that magnifies every social risk.

4. Specific Phobias – Fear That Disrupts Daily Life

Fear of snakes, flying, elevators, clowns, it may sound harmless until it isn’t. Specific phobias become problematic when the fear is so intense it interferes with your daily functioning. Avoiding a feared object or situation becomes a full-time job.

These types of anxiety disorders often stem from early experiences, media exposure, or learned behavior. While the fear might be irrational, the body’s response is very real, triggering the same fight-or-flight reactions as more complex disorders.

5. Obsessive-Compulsive Disorder (OCD) – An Intrusive Loop

OCD is one of the most misunderstood types of anxiety disorders. It’s not just about cleanliness or order. It’s about obsessions (unwanted, distressing thoughts) and compulsions (rituals or actions performed to neutralize them).

This loop can dominate a person’s day, checking locks 10 times, repeating phrases, or arranging objects “just right” to prevent imagined disasters. The goal of the compulsion is relief, but it never lasts. That’s what makes OCD so exhausting and persistent.

6. Post-Traumatic Stress Disorder (PTSD) – When the Past Isn’t Past

While most people associate PTSD with veterans, this disorder can affect anyone who’s experienced trauma, an accident, assault, loss, or even prolonged emotional abuse. Symptoms include flashbacks, nightmares, irritability, avoidance, and emotional numbness.

This type of anxiety disorder often goes undiagnosed because people assume they should’ve “moved on by now.” But trauma doesn’t work on a schedule. It lingers in the nervous system and resurfaces through everyday triggers, often when least expected.

7. Separation Anxiety Disorder – Not Just for Kids

Yes, adults can suffer from separation anxiety too. This disorder causes overwhelming fear or distress when being away from loved ones. It might show up as clingy behavior, difficulty sleeping alone, or excessive worry about others’ safety.

This type of anxiety disorder is deeply connected to attachment styles and emotional security. It often surfaces in romantic relationships or after a loss, and may be rooted in childhood experiences. Therapy can be very effective in helping adults manage this under-recognized form of anxiety.

When Should You Get Help?

Here’s the real test: Is your anxiety controlling your life, or are you in control?

If you’re avoiding events, losing sleep, struggling at work, or feeling constantly on edge, it’s time to consider professional help. According to the National Institute of Mental Health, nearly 20% of U.S. adults experience some form of anxiety disorder, but only a fraction seek support.

The earlier you recognize which of the types of anxiety disorders may be affecting you, the sooner you can get access to tools that bring relief, therapy, cognitive behavioral techniques, medication, or lifestyle changes.

Level Up Insight:

Anxiety disorders are not signs of weakness, they’re signs of a brain trying to protect you. But when that protection becomes overwhelming, it can sabotage the very life you’re trying to build. Learning about the types of anxiety disorders isn’t about boxing yourself in, it’s about breaking free. Once you name it, you can face it. And once you face it, you can transform your relationship with it. Don’t settle for survival when help is available. Level up, breathe deep, and remember: your peace is possible.

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Jonathan Anderson Appointed Sole Creative Director of Dior

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JWA-STORY (1)

In a historic move, Jonathan Anderson has been appointed as the sole Creative Director of Christian Dior, overseeing the brand’s men’s, women’s, and couture collections. This marks the first time since Christian Dior himself that a single designer has helmed all three lines, signaling a significant shift in the fashion house’s creative direction.

Delphine Arnault, Chair and CEO of Christian Dior Couture, expressed enthusiasm about Anderson’s appointment, highlighting his extensive experience within LVMH and his deep understanding of Dior’s heritage. Arnault stated, “Jonathan Anderson is going to be the head of creation for Dior, across men’s and women’s, couture and accessories.” She emphasized that Anderson’s clear vision and creative prowess make him an ideal fit to lead Dior into its next chapter.

Anderson’s journey to Dior began in April 2025 when he was confirmed as the Artistic Director of Dior’s men’s collections. Prior to this, he had a distinguished tenure at Loewe, where he served as Creative Director from 2013 until his departure in early 2025. During his time at Loewe, Anderson revitalized the brand, introducing innovative designs and collaborations that resonated with a global audience. Notably, he played a pivotal role in transforming Loewe into a cultural powerhouse, with his designs and campaigns garnering widespread acclaim.

At Dior, Anderson is poised to bring his unique vision and aesthetic sensibilities to the storied fashion house. His appointment is seen as a strategic move to unify Dior’s creative direction and reinvigorate its presence in the fashion industry. The fashion world eagerly anticipates Anderson’s debut collection, which is expected to showcase his signature blend of innovation and craftsmanship.

As Dior embarks on this new creative journey under Anderson’s leadership, the industry watches closely to see how his influence will shape the future of one of fashion’s most iconic brands.

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Can TikTok’s ‘Fibermaxxing’ Trend Really Help You Lose Weight? Experts Weigh In

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TikTok trends often ride the waves of wellness fads, but every so often, one garners attention for the right reasons. The latest in that category is “fibermaxxing”  a trend encouraging people to bulk up their diets with fiber-rich foods like vegetables, fruits, whole grains, and legumes.

But while social media influencers are diving headfirst into the produce aisle, nutrition experts are urging a more balanced, informed approach. So, is fibermaxxing just a fad, or could it be your secret weapon for long-term health and sustainable weight loss?

What Is Fibermaxxing?

Fibermaxxing is the practice of intentionally adding more fibre to your daily meals and snacks. This includes everything from starting your day with chia-packed oats to tossing kale, beans, and whole grains into lunch and dinner plates.

Unlike restrictive diets, fiber-emphasizing emphasises abundance, loading up on nutrient-dense, plant-based foods that naturally contain both soluble and insoluble fiber.

According to Kara Landau, RD, of the Gut Feeling Consultancy, this trend “is actually a very positive direction for people’s eating patterns” and aligns with traditional nutrition advice.

Why Fiber Matters

Fiber is a non-digestible carbohydrate found in plant foods. It plays a crucial role in digestion, helps regulate blood sugar levels, lowers cholesterol, and feeds beneficial gut bacteria.

Moreover, fiber promotes satiety, meaning you feel fuller for longer after eating. This effect can reduce overall calorie intake and help with weight loss or maintenance — a key reason it’s caught fire on platforms like TikTok.

Dahlia Marin, RDN, emphasizes that fiber-rich diets also regulate hormones that influence mood and weight, support healthy digestion, and may help prevent chronic diseases like:

  • Type 2 diabetes

  • Heart disease

  • Colorectal cancer

In fact, high-fiber diets are even linked to longevity and healthy aging, especially in women, according to recent research.

How Much Fiber Do You Really Need?

The recommended daily intake of fiber varies by age and sex:

  • Men under 50: 38 grams/day

  • Women under 50: 25 grams/day

  • Men over 50: 30 grams/day

  • Women over 50: 21 grams/day

  • Children: 14–25 grams/day, depending on age

However, studies show that most people fall short of these goals—consuming far less than the minimum daily requirement.

That’s where fibermaxxing can offer real value—by encouraging people to close this gap.

Can-TikTok’s-‘Fibermaxxing’-Trend-Really-Help--You

Can-TikTok’s-‘Fibermaxxing’-Trend-Really-Help–You

The Right Way to Start Fibermaxxing

While fibermaxxing is healthy in principle, jumping into a high-fiber lifestyle too fast can cause bloating, gas, or discomfort — especially for people with sensitive digestive systems.

Experts recommend:

  • Start slow: Gradually increase fiber over several days or weeks

  • Drink more water: Helps fiber move through the digestive tract

  • Choose variety: Mix soluble and insoluble fibers from diverse food sources

Some go-to options include:

  • Chia seeds

  • Kiwi

  • Sweet potatoes

  • Lentils and legumes

  • Whole grains like oats and quinoa

  • Broccoli, kale, and other leafy greens

  • Berries, apples, and avocados

Reading labels on packaged foods is also key. Look for multiple fiber sources, not just isolated ones like chicory root or soluble corn fiber.

Who Should Be Cautious?

Despite its benefits, fibermaxxing may not be suitable for everyone.

Those with conditions like:

  • Irritable Bowel Syndrome (IBS)

  • Inflammatory Bowel Disease (IBD)

  • Small Intestinal Bacterial Overgrowth (SIBO)

  • Short Bowel Syndrome

…might need to adjust fiber intake slowly and consult a healthcare professional before jumping in.

Older adults, too, may experience more sensitive digestion and require a personalized approach. Some may even benefit from a reverse elimination diet—a method that strategically reintroduces fiber after a gut reset.

Not Just a Trend — A Lifestyle Shift

Unlike many TikTok fads that prioritize aesthetics over health, fibermaxxing is grounded in clinical science. It’s not about eliminating food groups or starving the body — it’s about fueling it smarter.

It may support weight loss not by restricting calories, but by improving satiety, hormone balance, and gut health, all while lowering the risk of chronic disease.

Still, fibermaxxing should be approached thoughtfully. More is not always better, especially when it comes to gut health.

As with most dietary changes, the key to success is personalization: listen to your body, diversify your food sources, and take it one meal at a time.

If you’re ready to add more fiber to your life, fibermaxxing might be a smart and sustainable way to do it. Just remember: balance, variety, and hydration are your best friends.

With a little planning, this TikTok trend can go from a viral moment to a lifelong habit that helps you feel fuller, lighter, and healthier.

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Miley Cyrus Opens Up About ‘Excruciating’ Ovarian Cyst Rupture

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Miley Cyrus Opens Up About ‘Excruciating’ Ovarian Cyst Rupture:

In a raw and powerful interview with Apple Music 1’s The Zane Lowe Show, pop icon Miley Cyrus shared an experience many women may relate to  but few talk about. While ringing in the new year with country legend Dolly Parton on her live TV special, Cyrus suffered a medical emergency that she later revealed was the rupture of an ovarian cyst.

The 32-year-old performer described the pain as excruciating, calling the incident “traumatic.” Despite the severity of the situation, she finished the show. “We didn’t know exactly what was going on,” Cyrus said. “It was really, really hard on me.”

Her openness is shedding light on a health condition that affects countless women globally but often goes unnoticed or misunderstood.

What Are Ovarian Cysts?

Ovarian cysts are fluid-filled sacs that form on or inside an ovary, and they’re particularly common during a woman’s reproductive years. Most of the time, these cysts are benign and resolve on their own without any symptoms. These are known as functional cysts, and they typically form during ovulation as part of the menstrual cycle.

However, not all cysts are harmless. According to Dr. Yen Hope Tran, OB-GYN at MemorialCare Orange Coast Medical Center, other types — such as dermoid cysts, endometriomas, and cystadenomas — may become problematic. These complex cysts can grow larger, cause persistent pain, and in some cases, rupture or lead to ovarian torsion, a potentially dangerous condition where the ovary twists on itself.

Warning Signs You Shouldn’t Ignore

Many ovarian cysts are asymptomatic, but certain symptoms can be early warning signs that something more serious is happening. These include:

  • Dull or sharp pain in the lower abdomen (usually on one side)

  • Bloating or a sense of pressure

  • Irregular menstrual cycles

  • Pain during or after intercourse

  • Frequent need to urinate (due to pressure on the bladder)

If a cyst ruptures, symptoms can escalate quickly. Sudden, severe pelvic pain, nausea, vomiting, dizziness, or fainting can signal internal bleeding — and require emergency medical attention.

Dr. Tran emphasizes the importance of recognizing when a cyst moves from manageable to dangerous. “Seek emergency care if you experience sudden and severe abdominal pain, especially if it’s accompanied by fainting, rapid heartbeat, or signs of internal bleeding.”

Miley Cyrus Opens Up About ‘Excruciating’ Ovarian Cyst Rupture:

Miley Cyrus Opens Up About ‘Excruciating’ Ovarian Cyst Rupture:

What Else Can Mimic a Cyst?

The symptoms of ovarian cysts can overlap with many other medical conditions. Appendicitis, ectopic pregnancy, urinary tract infections, and even gastrointestinal issues like IBS or diverticulitis may present similarly. That’s why a proper pelvic exam and imaging, often via a transvaginal ultrasound, are key to diagnosis.

Treatment Options

For many, ovarian cysts don’t require any intervention. Regular monitoring may be all that’s needed, especially in premenopausal women. Hormonal birth control can help prevent recurrence of certain types of cysts.

If the cyst is large, complex, or persistent — or if it causes significant pain — surgery may be recommended. In the case of a rupture, conservative management with pain relief and observation is sometimes enough. But more serious cases involving internal bleeding or infection might demand hospitalization or emergency surgery.

When to Worry

Cysts that grow rapidly, appear complex in imaging, or develop in postmenopausal women warrant closer attention. “We assess risk using ultrasounds, blood tests like CA-125, and the patient’s symptoms,” says Dr. Tran.

Unfortunately, awareness remains low, especially among younger women. Celebrities like Miley Cyrus, Hailey Bieber, Lena Dunham, and Kate Beckinsale opening up about their health journeys are helping to break the silence and spark important conversations.

The Bigger Picture: Listening to Your Body

Cyrus’s experience highlights a key message  listen to your body and don’t downplay serious symptoms. Pain, especially when it’s intense and unexplained, deserves medical evaluation.

By continuing her performance despite a medical emergency, Cyrus demonstrated incredible strength. But her story also reminds us that enduring pain shouldn’t be normalized, especially when it could be a sign of something serious.

As more women speak up, the stigma around reproductive health is beginning to lift. Let this moment be more than a headline — let it be a catalyst for awareness, education, and proactive healthcare.

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Why We Fear Fresh: How “Healthy = Spoils Fast” Is Hurting Our Habits

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How “Healthy = Spoils Fast” Is Hurting Habits Level

You walk into the grocery store with the best intentions: Greek yoghurt, fresh berries, leafy greens, maybe some hummus. But as you reach for that tub of spinach, a voice in your head whispers, “Will it go bad before I even open it?”

If that sounds familiar, you’re not alone.

A new study has uncovered a surprising psychological barrier that’s preventing people from eating healthier: the fear that nutritious food spoils faster.

And while it might seem harmless at first, this misperception is influencing shopping decisions, increasing food waste, and even nudging consumers toward processed alternatives.

The Spoilage Paradox

The study, conducted by behavioural scientists at a leading university, surveyed thousands of consumers across grocery aisles and at home. The results were clear: people consistently believe that “healthy” foods are more perishable than less healthy ones.

From organic yoghurt to fresh-cut veggies, anything perceived as wholesome was also perceived as ephemeral.

“This mental shortcut seems rooted in the idea that if a product has fewer preservatives or is more natural, it must spoil faster,” explains Dr. Meredith Lang, the lead researcher. “And while that’s sometimes true, it’s not a rule, and the assumption is leading to irrational decisions.”

Healthy Doesn’t Always Mean Fragile

In reality, not all healthy food spoils at lightning speed.

  • Apples can last weeks in a cool place.

  • Greek yoghurt, especially when unopened, stays good well past its date.

  • Carrots, beets, and even leafy greens can remain crisp with proper storage.

And yet, the fear persists. What’s worse, many consumers throw out healthy items prematurely, worried about safety or taste, even when the food is still perfectly edible.

How “Healthy = Spoils Fast” Is Hurting Habits Level

How “Healthy = Spoils Fast” Is Hurting Habit Level

Marketing Cues and Mind Games

Part of the blame may lie in product labelling and marketing language.

Words like “natural,” “organic,” or “fresh” can subconsciously signal fragility. A non-GMO label or minimal-ingredient list might inspire trust but also trigger concern over shelf life.

Contrast that with highly processed snacks, which often appear in sturdy packaging with multi-month expiration dates. They project security, even if they lack nutrition.

“It’s about perceived risk,” Lang says. “People would rather toss a slightly wilted kale bunch than risk eating something’ bad.’ But this tendency means we waste food that’s still safe and nourishing.”

Convenience Wins Even at a Cost

This fear-driven behaviour has real-world implications. Consumers often skip the produce aisle entirely, opting for items that feel “safer” or longer-lasting: granola bars, frozen meals, or prepackaged snacks.

This bias also favours ultra-processed foods, which may be more shelf-stable but are also linked to increased risks of obesity, heart disease, and chronic illness when consumed regularly.

Ironically, in trying to avoid spoilage, consumers might be sacrificing their long-term health.

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Mosquitoes on Medicine: A Revolutionary Malaria Strategy Emerges

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Mosquitoes on Medicine A Revolutionary Malaria and

What if the best way to stop malaria isn’t by killing mosquitoes but by healing them?

In a twist that turns conventional thinking on its head, researchers at Harvard University have proposed a radical new approach to combat one of the deadliest diseases in the world: give mosquitoes the medicine. Yes, you read that right. Instead of targeting malaria by eliminating mosquitoes, scientists want to treat the insects with anti-malarial drugs effectively turning them into harmless carriers.

This fresh perspective comes as malaria continues to devastate communities, particularly in sub-Saharan Africa, claiming nearly 600,000 lives each year  the majority being young children. Traditional tactics, such as insecticide-treated bed nets and vaccines, have helped, but there’s a growing problem: resistance. Mosquitoes are evolving, and insecticides are no longer packing the punch they used to.

So, what’s the breakthrough?

Target the Parasite, Not the Carrier

The Harvard team, led by Dr. Alexandra Probst, took a deep dive into the genetics of the malaria parasite while it’s inside the mosquito. Their goal? Identify a weak spot. After testing a vast library of drug candidates, they narrowed the list to 22 promising compounds, and two of them completely killed the parasite within the mosquito.

The key lies in how the drugs are delivered. Instead of injections or bait, these compounds are absorbed through the mosquito’s legs a process tested by simulating contact with treated surfaces like bed nets. When a mosquito lands on a net coated with the drug, it absorbs enough of the compound to wipe out any malaria parasites inside it.

It’s an elegant solution. Even if the mosquito survives contact with the net and goes on to bite someone, it can no longer transmit malaria.

Mosquitoes on Medicine A Revolutionary Malaria and

Mosquitoes on Medicine A Revolutionary Malaria and

A Game-Changer for Bed Nets

Bed nets have long been a cornerstone of malaria prevention, offering both physical protection and chemical protection. But as mosquito populations build resistance to insecticides, the nets lose effectiveness. The new vision is to enhance them: combine traditional insecticides with anti-malarial drugs, ensuring a backup plan if one method fails.

“The idea is that we’re not just trying to kill mosquitoes anymore,” says Dr. Probst. “We’re actually treating them almost like turning them into unwitting allies in the fight against malaria.”

Even more exciting? The drug treatment on the nets has been shown to last up to a year in laboratory conditions, making it potentially more cost-effective than constantly reapplying insecticides.

Why This Could Work

One of the reasons malaria is so difficult to control is the high number of parasites in an infected human, often billions. But a mosquito typically carries fewer than five parasites. That makes the chance of resistance evolving within the mosquito population much lower.

In essence, it’s like targeting the parasite in its most vulnerable state.

What Comes Next?

Of course, laboratory success doesn’t always translate to real-world effectiveness. That’s why the next phase of research is already planned: field trials in Ethiopia. These will determine how well the drug-coated nets work in homes, villages, and communities most affected by malaria.

It could take up to six years for all the studies and trials to be completed and approved. But the potential payoff is massive a safer, longer-lasting, and possibly more affordable method of malaria prevention.

The vision is clear: a future where mosquito bites no longer mean danger and where the battle against malaria can be fought with innovation rather than extermination.

Your Role in the Story

This story isn’t just for scientists or doctors it’s about the global community uniting to tackle one of the world’s oldest plagues. You can:

  • Support organisations funding malaria research.

  • Stay informed about global health innovations.

  • Share groundbreaking ideas like this to keep momentum going.

Because progress begins not just with invention but with awareness.

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Fuel Your Body Naturally: Celebrity Fitness Expert Yasmin Karachiwala’s Guide to Boosting Protein Intake

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In our fast-paced lives, where convenience often dictates our food choices, one essential nutrient frequently gets overlooked: protein. This vital macronutrient plays a crucial role in building lean muscle, supporting metabolism, reducing cravings, and keeping you satiated longer. The good news? You don’t need drastic dietary overhauls or expensive supplements to enhance your protein intake. Celebrity fitness expert Yasmin Karachiwala shares simple, natural ways to incorporate more protein into your meals, making healthy eating both accessible and enjoyable.

1. Almonds: The Perfect On-the-Go Snack

Almonds are a powerhouse of high-quality protein, offering approximately 6 grams per 28-gram serving. Beyond protein, they are rich in healthy fats, fibre, vitamin E, and magnesium, contributing to overall wellness. Whether you’re between meetings, heading to a workout, or need a midday pick-me-up, a handful of almonds provides a compact, convenient, and nourishing snack.

Greek yoghurt contains nearly twice the protein of regular yoghurt and is rich in probiotics that support gut health. Versatile in its use, it can be enjoyed on its own, topped with fruits and nuts, blended into smoothies, or transformed into a savoury dip. It’s an indulgent yet nourishing option for a mid-morning snack or post-workout meal.

3. Fish: Lean Protein with Omega-3 Benefits

For non-vegetarians, fish such as salmon, tuna, and mackerel are excellent sources of lean protein and omega-3 fatty acids, which are beneficial for heart and brain health. Grilled or baked, fish makes a smart protein choice for lunch or dinner, providing essential nutrients without being too heavy.

4. Soya Chunks: A Plant-Based Protein Hero

Soya chunks are a fantastic plant-based protein option, especially for vegetarians. They are rich in protein and can be easily incorporated into various dishes, from curries to stir-fries. Their versatility and high protein content make them a valuable addition to any meal.

5. Sprouts: Nutrient-Dense and Easy to Add

Sprouts are another excellent plant-based protein source. They are nutrient-dense and can be added to salads, sandwiches, or eaten as a snack. Including sprouts in your meals not only boosts protein intake but also adds a fresh, crunchy texture.

fuel-your-body-naturally-celebrity-fitness-yasmin

fuel-your-body-naturally-celebrity-fitness-yasmin

6. Incorporate Protein-Rich Vegetables

Vegetables like Brussels sprouts and spinach are surprisingly high in protein. Brussels sprouts provide about 3 grams of protein per cooked cup, while spinach offers around 5 grams per cooked cup. These vegetables are also rich in vitamins and antioxidants, making them a healthy addition to your diet.

7. Smart Snacking and Meal Planning

Incorporating protein-rich snacks like nuts, seeds, and yoghurt can help maintain energy levels throughout the day. Planning meals to include a balance of protein sources ensures that your body receives the nutrients it needs for optimal function.

8. Portion Control for Optimal Intake

Practicing portion control is essential for maintaining a balanced diet. Using kitchen scales or portion-size guides can help ensure adequate protein consumption without overeating. Distributing protein intake evenly across meals helps stabilise blood sugar levels and keeps cravings at bay.

9. Diversify Your Protein Sources

Relying on a single protein source can be limiting. Including a variety of protein-rich foods like fish, eggs, dairy, lentils, tofu, beans, and nuts in your meals ensures a well-rounded intake of essential amino acids and nutrients.

10. Embrace Plant-Based Proteins

Plant-based proteins are not only beneficial for vegetarians but also offer health advantages for everyone. Foods like legumes, beans, lentils, and tofu are cost-effective, nutrient-dense, and support muscle growth when paired with a balanced diet. By making these simple adjustments to your meals, you can naturally increase your protein intake, supporting overall health and well-being. Remember, it’s not about drastic changes but about making mindful choices that align with your lifestyle and nutritional needs.

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The Rise of THC Beverages : You Can Drink Your Weed Now

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Imagine cracking open a cold can of beer or soda, but of cannabis THC beverage is just like that. It fizzes, it tastes like a summer spritz, and 20 minutes later, you’re feeling the high. Welcome to the bold new world of THC-infused beverages, where getting lifted comes in a sleek aluminium can.

What started as a niche product for curious cannabis lovers is now a booming industry. Across the U.S., especially in states where recreational marijuana is legal, dispensaries and even some mainstream beverage stores are lining their shelves with colourful cans promising relaxation, euphoria, and a hangover-free alternative to alcohol. With health-conscious millennials and Gen Zers reducing their alcohol intake, THC drinks are stepping up as the cool new vice.

How THC Beverages Work

Unlike traditional edibles like brownies or gummies, THC beverages are designed to work faster. Most contain nano-emulsified THC, meaning the psychoactive compound is broken down into tiny particles that your body absorbs more quickly than oil-based edibles. The result? You might start feeling something in just 15 to 30 minutes.

But don’t expect the rocket-launch intensity of a joint. These drinks tend to be microdosed, often ranging from 2.5 to 10 milligrams of THC per can. That makes them ideal for social use, especially for people who want a light buzz without the harshness of smoking or the unpredictability of edibles.

What’s Inside the Can?

The ingredients vary, but many of these beverages blend sparkling water or juice with cannabis extracts. Some brands add adaptogens, herbs, or even caffeine to make their drinks more energising or calming. You’ll find two major types: ones with THC (the compound that gets you high) and others with CBD (which doesn’t intoxicate but may promote relaxation).

Some drinks contain both, offering what’s known as the “entourage effect”—a synergistic blend of cannabinoids that enhances the overall experience.

The Buzz vs. The Booze

Here’s where it gets interesting: More and more people are swapping their glass of wine for a can of cannabis. Why? Fewer calories, no hangover, and a more mellow high.

In fact, some beverage companies have started branding THC drinks as “California Sober,” meaning you don’t drink alcohol but are open to using cannabis or psychedelics. And in social situations, these drinks are proving to be great icebreakers, especially for non-smokers who don’t want to inhale anything but still want to join the fun.

The-Rise-of-THC-Beverages-You-Can-Drink-Your-Weed

The-Rise-of-THC-Beverages-You-Can-Drink-Your-Weed

Risks and Warnings

As fun as it sounds, sipping your weed isn’t risk-free.

First, these drinks can sneak up on you. Just because it doesn’t hit instantly like a joint doesn’t mean you should down two cans back-to-back. Overconsumption can lead to paranoia, anxiety, and nausea, especially for newbies.

Second, dosage matters. Always check the THC content on the label. For first-timers, start with no more than 2.5 mg and wait at least 45 minutes before deciding to drink more.

Also worth noting: Driving after consuming a THC beverage is still driving under the influence. And even in states where cannabis is legal, there are rules about public consumption.

Legal Grey Zones

THC beverages are only legal in states where recreational cannabis is permitted. In other states, you might find hemp-derived delta-8 THC drinks, which exist in a legal grey area and are often less predictable in effect.

If you’re travelling, check the local laws before packing your cannabis cooler.

The Future of the Highball?

With big beverage brands like Molson Coors and Constellation Brands investing in cannabis drink startups, it’s clear this isn’t just a passing trend. Experts predict that THC beverages could be the next billion-dollar category, especially as more states and countries relax cannabis laws.

Imagine ordering a THC mojito instead of a cocktail at your favourite rooftop bar. Or enjoying a cannabis mimosa at brunch. The future is intoxicating and a little fizzy.

Drinking your weed might sound like a stoner fantasy, but it’s fast becoming a lifestyle choice for the health-conscious, socially savvy consumer. Whether you’re seeking a smoother high, an alcohol alternative, or just want to join the next wave of cannabis culture, THC drinks offer a new way to toast to life.

Just remember: sip slowly, stay safe, and enjoy the ride.

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Health & Wellness

MomentM: The Ayurveda-Inspired Supplement Brand Bringing Clarity to Wellness Chaos

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In a wellness industry overcrowded with endless options, influencer noise, and questionable claims, Ayurveda Inspired MomentM is making its debut with a simple yet powerful promise — to bring clarity, balance, and intention back to health and self-care.

Founded by Marise Saldanha, a former brand manager at Dove and a wellness seeker herself, MomentM is an Ayurveda-inspired, science-backed supplement line aiming to streamline the consumer experience. The brand launches with four thoughtfully crafted products, each designed to support a core aspect of well-being: mind, body, and vitality.

“Our product philosophy is based around the three Ayurvedic pillars — mind, body, and vitality — which are seen as the core elements of the universe,” said Saldanha. “Each one constantly influences the other, and our formulas reflect that interconnection.”

MomentM’s four flagship products are:

  • Calm ($40): A lavender latte-flavoured gummy designed to help destress and support mental clarity.

  • Synthesis ($60): A peach-plum collagen and hyaluronic acid powder promoting skin health and hydration.

  • Equilibrium ($60): A pre-, pro-, and post-biotic capsule aimed at restoring gut health.

  • Revitalise ($80): A blend of ceramosides, hyaluronic acid, and antioxidants formulated to boost skin glow and elasticity.

Each product features a careful balance of traditional Ayurvedic ingredients and modern, clinically supported compounds, ensuring the best of both worlds. MomentM is backed by Marksans Pharma, the Indian pharmaceutical giant led by Saldanha’s father, which also provides formulation guidance and rigorous testing.

While all products are manufactured in California, the brand’s ethos is deeply rooted in Saldanha’s Indian upbringing and her early exposure to holistic health. Growing up around Ayurveda and plant-based healing traditions gave her a grounding that she leaned into when her own wellness journey took an unexpected turn.

Ayurveda Inspired MomentM Supplement Brand Industry

Ayurveda Inspired MomentM Supplement Brand Industry

From Overwhelm to Opportunity

Saldanha’s wellness awakening began like many — with curiosity and excitement — but quickly spiraled into confusion. During her time at the Haas School of Business at UC Berkeley, she dove headfirst into the world of supplements, influenced by a flood of wellness content and aspirational health claims.

“What started as a journey to feel better ended up making me feel worse,” she shared. “My cabinet was overflowing with supplements — some expired, some half-used, most of them ineffective or even harmful.”

At one point, after trying multiple products with conflicting benefits, Saldanha began experiencing severe stomach pain and burnout, both mentally and physically.

“I remember lying in bed, thinking I should’ve never started this in the first place,” she recalled. “That moment of pain led to the clarity I needed — we don’t need more products, we need better ones.”

This personal revelation was the genesis of MomentM — a brand focused not on overwhelming consumers, but empowering them with clarity. It isn’t about selling dozens of trendy pills; it’s about reconnecting people to intentional, synergistic wellness.

Backed by Science, Grounded in Tradition

One of MomentM’s defining advantages is its backing by a pharmaceutical company. Marksans Pharma’s involvement ensures pharmaceutical-grade formulations, quality testing, and consistent ingredient integrity — a rarity in a space often dominated by marketing hype.

“The level at which we test is very rigorous,” Saldanha said. “It’s one of our greatest strengths, but also a major challenge in getting things just right.”

MomentM’s dual approach — using both botanicals like ashwagandha and turmeric as well as modern actives like ceramosides and hyaluronic acid — sets it apart in the supplement space. Every formula undergoes stability testing, clinical research review, and dosage verification before it hits the shelves.

The Future of MomentM

The brand plans to expand its offerings by the end of the year, with four new SKUs on the horizon — including a cognition-supporting gummy that aligns with its “mind, body, vitality” mantra.

Though the company has chosen not to disclose exact sales projections, around $3 million has been invested in building the brand infrastructure, product development, and marketing launch.

As the wellness industry continues to grow, MomentM enters not just as another supplement label but as a movement toward simplification, authenticity, and cultural integrity.

“We’re not here to be part of the noise,” Saldanha said. “We’re here to give people a genuine alternative — one that honors both ancient wisdom and modern science.”

 

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Health & Wellness

Traditional Diet Could Be the Medicine to Reducing Inflammation and Health Diseases

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In a world increasingly dominated by ultra-processed Diet, emerging research is reminding us of something our ancestors likely knew well food is medicine. A recent study published in Nature Medicine sheds light on the profound and rapid impact our diet choices can have on immune function, inflammation, and long-term health.

The Study at a Glance

Conducted by researchers from Radboud University Medical Centre and Kilimanjaro Christian Medical University College, this study focused on young men from the Kilimanjaro region in Northern Tanzania. Participants were split into three groups to compare the effects of a traditional African diet and a modern Western-style diet on inflammation and metabolic health.

  • One group switched from their traditional Kilimanjaro diet to a Western-style diet for two weeks.

  • A second group transitioned from a Western-style diet to a traditional African diet.

  • A third group, also on a Western diet, consumed Mbege — a traditional fermented drink made from bananas and millet — for one week.

The findings were clear: just two weeks of eating a Western diet increased markers of inflammation and weakened immune response. Conversely, switching to a traditional, plant-based diet or incorporating fermented foods led to notable anti-inflammatory effects.

What Makes the Traditional African Diet So Powerful?

The traditional African diet followed by the rural participants was rich in:

  • Green leafy vegetables

  • Legumes

  • Root vegetables like cassava and sweet potatoes

  • Plantains

  • Ancient grains such as millet and sorghum

  • Black tea

These foods are naturally high in dietary fibre and bioactive compounds such as polyphenols, which support a healthy gut microbiome and promote anti-inflammatory processes in the body. The high-fibre content helps nurture beneficial gut bacteria, which in turn generate metabolites that regulate immune and metabolic functions.

Fermented Foods: A Microbial Boost

One particularly interesting aspect of the study was the inclusion of Mbege, a traditional fermented banana beverage. Even after just a week of consumption, participants who drank Mbege experienced improved immune markers. This is likely due to the presence of beneficial microbes and plant compounds like flavonoids, which help modulate inflammation and enhance vascular and immune health.

According to Dr. Thomas M. Holland from the RUSH Institute for Healthy Ageing, fermented foods play a critical role in enriching the gut microbiome — something that Western diets, with their lack of microbial diversity, fail to support.

Traditional Diet Could Be the Medicine to a Reducing Illness

Traditional Diet Could Be the Medicine to a Reducing Illness

What’s Wrong with the Western Diet?

The Western diet adopted in the study consisted of:

  • Processed meats

  • Pizza

  • Fried chicken and French fries

  • Pancakes and white bread

  • Refined carbohydrates like spaghetti

These foods are typically low in fibre and antioxidants and high in refined sugars, unhealthy fats, and additives that can trigger inflammation. Dr. Holland explains that these diets promote oxidative stress, disrupt gut microbiota, and negatively affect immune regulation.

In the study, participants who switched to the Western diet showed a rise in inflammatory proteins in the blood, altered gene expression, and reduced ability of immune cells to respond to threats.

A Wake-Up Call for Urbanized Diets

Urbanisation in Africa and globally is leading more people to shift from traditional eating patterns to convenient, processed Western-style meals. But as this study shows, even a short period on a Western diet can have measurable health consequences.

Meanwhile, incorporating traditional diets, be it African, Mediterranean, or Latin American, may offer a powerful shield against modern-day diseases like type 2 diabetes, cardiovascular issues, and obesity-related inflammation.

Dr. Quirijn de Mast, lead author of the study, emphasised that traditional African diets are just as insightful and beneficial as better-known diets like the Mediterranean or Japanese. He believes preserving traditional dietary practices is not only culturally significant but also crucial for public health.

This study reinforces a compelling message: food can either inflame or heal. Diets rich in plants, whole foods, and fermented ingredients can dramatically improve immune and metabolic health in a matter of weeks.

In contrast, diets heavy in processed and refined foods push the body into a chronic inflammatory state, laying the groundwork for a host of lifestyle-related diseases.

The solution may be simpler — and more traditional — than we think.

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